Pathophysiology of Myelodysplastic Syndromes

Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes.Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells.Deletion and mutations Drop Leaf Table trigger epigenetic modifications, and co-transcriptional and post-transcriptional deregulat

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First Report of IMI-2-Producing Enterobacter bugandensis and CTX-M-55-Producing Escherichia coli isolated from Healthy Volunteers in Tunisia

The aim of this study was to characterize the prevalence of fecal carriage of extended-spectrum beta-lactamases and carbapenemase-producing Gram-negative bacteria among healthy humans in Tunisia.Fifty-one rectal swabs of healthy volunteers were plated on MacConkey agar plates supplemented with cefotaxime or imipenem.The occurrences of resistance ge

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A general theory of glacier surges

We present the first general theory of glacier surging that includes both temperate and polythermal glacier surges, based on coupled mass and enthalpy budgets.Enthalpy (in the form of thermal energy and water) is gained at the glacier bed from geothermal heating plus frictional heating (expenditure of potential energy) as a consequence of ice flow.

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Initial clinical experience of Stereotactic Body Radiation Therapy (SBRT) for liver metastases, primary liver malignancy, and pancreatic cancer with 4D-MRI based online adaptation and real-time MRI monitoring using a 1.5 Tesla MR-Linac.

Purpose/objectivesRecently a 1.5 Tesla MR Linac has been FDA approved and is commercially available.Clinical series describing treatment methods and outcomes for upper abdominal tumors using a 1.5 Tesla MR Linac are lacking.We present the first clinical series of upper abdominal tumors treated using a 1.5 Tesla MR Linac along with the acquisition o

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